Take your dose of Fildena Purple about one hour before you intend to have sex.
A: The maximum recommended dose for Fildena
(sildenafil), used to treat ED (erectile dysfunction), is 100mg per day. The
drug information above is an informational resource designed to assist licensed
healthcare practitioners in caring for their patients and/or to serve consumers
viewing this service as a supplement to, and not a substitute for, the
expertise, skill, knowledge and judgment of healthcare practitioners. Prolonged
erection greater than 4 hours and priapism (painful erections greater than 6
hours in duration) have been reported infrequently since market approval of
Fildena. To decrease the chance of adverse reactions in patients taking
ritonavir, a decrease in sildenafil dosage is recommended see DOSAGE AND
ADMINISTRATION , DRUG INTERACTIONS , and CLINICAL PHARMACOLOGY.
Sildenafil
is also marketed as REVATIO for the treatment of PAH. Fildena is contraindicated
in patients with a known hypersensitivity to sildenafil, as contained in Fildena
and REVATIO, or any component of the tablet. The erectile response, as assessed
by RigiScan®, generally increased with increasing sildenafil dose and plasma
concentration.
Although plasma levels of sildenafil at 24 hours post dose
are much lower than at peak concentration, it is unknown whether nitrates can be
safely co-administered at this time point see CONTRAINDICATIONS. Blood pressure
was measured immediately pre-dose and at 15, 30, 45 minutes, and 1, 1.5, 2, 2.5,
3, 4, 6 and 8 hours after Fildena or matching placebo. In the second study, a
single oral dose of Fildena 50 mg or matching placebo was administered in a
2-period crossover design to 20 generally healthy males with BPH.

For the 19 subjects who received both Fildena and matching placebo, the
placebo-subtracted mean maximum decreases from baseline (95% CI) in systolic
blood pressure were as follows: There was one subject with a decrease from
baseline in standing systolic BP > 30mmHg following Fildena 50 mg and one
subject with a decrease from baseline in standing systolic BP > 30 mmHg
following both Fildena 50 mg and placebo. Two were discontinued after study
period 1: one failed to meet pre-dose screening qualifications and the other
experienced symptomatic hypotension as a moderately severe adverse event 30
minutes after dosing with open-label Fildena 50 mg. Of the twenty subjects who
were ultimately assigned to treatment, a total of 13 subjects successfully
completed dose period 1, and seven had successfully completed the previous
doxazosin study https://www.drvolcanoe.com/fildena-side-effects/ (using Fildena
50 mg).
All three were taking Fildena 100 mg, and all three reported mild
adverse events at the time of reductions in standing SBP, including vasodilation
and lightheadedness. When Fildena 100 mg oral was co-administered with
amlodipine, 5 mg or 10 mg oral, to hypertensive patients, the mean additional
reduction on supine blood pressure was 8 mmHg systolic and 7 mmHg diastolic. The
maximum observed decrease in diastolic blood pressure was -17.2 mmHg when
sildenafil was co-administered with alcohol versus -11.1 mmHg when alcohol was
administered alone.
Studies have produced relevant data on the effects of
Fildena on cardiac output In one small, open-label, uncontrolled, pilot study,
eight patients with stable ischemic heart disease underwent Swan-Ganz
catheterization.
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